🔬 What is Lenvatinib?
Lenvatinib is a potent multi-kinase inhibitor used for:
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Differentiated Thyroid Cancer (DTC) unresponsive to radioactive iodine
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Advanced Renal Cell Carcinoma (RCC), usually in combination with pembrolizumab
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Hepatocellular Carcinoma (HCC) in previously untreated cases
It is an oral targeted anti-cancer medication that blocks tumor cell growth and disrupts tumor blood supply by inhibiting specific receptors involved in angiogenesis (VEGFR, FGFR, PDGFR).
💊 Available Strengths:
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Lenvatinib 4mg Capsules
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Lenvatinib 10mg Capsules
Each capsule is manufactured under strict international quality standards and prescribed by oncologists globally.
✅ Key Benefits:
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Approved for multiple advanced cancers
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Slows cancer progression effectively
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Can be taken orally at home
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Available in combo therapy (with Pembrolizumab or Everolimus)
🧬 How Lenvatinib Works:
Lenvatinib works by blocking multiple kinase enzymes responsible for the growth of cancer cells and formation of new blood vessels (angiogenesis). This helps reduce tumor size and improves overall survival in late-stage cancers.
🛒 Why Buy From PalmerWellness.com?
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Only genuine, doctor-approved medicines
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Global shipping with discreet packaging
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Personalized support for oncology prescriptions
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📦 Dosage & Packaging:
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Strengths: 4mg & 10mg
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Standard Pack Sizes: 10 or 30 capsules per pack
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Manufacturer: Natco, Eisai, Cipla, etc.
⚠️ Precautions:
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Take exactly as directed by your oncologist
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Do not self-medicate or adjust dosage
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Common side effects: high blood pressure, fatigue, diarrhea, weight loss
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Not for use in pregnancy; contraception advised
🧴 Storage:
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Store below 25–30°C
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Keep away from moisture
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Keep out of children’s reach
Frequently Asked Questions (FAQ) for Lenvatinib (4mg / 10mg) in the Philippines
Understanding Lenvatinib and Its Use
1. What is Lenvatinib and what types of cancer is it used for in the Philippines?
Lenvatinib is a potent oral targeted therapy drug known as a multi-kinase inhibitor. In the Philippines, oncologists prescribe it to treat several types of advanced cancers, including:
- Differentiated Thyroid Cancer (DTC) that is resistant to radioactive iodine treatment.
- Renal Cell Carcinoma (RCC), a type of kidney cancer, often in combination with other drugs.
- Hepatocellular Carcinoma (HCC), the most common type of primary liver cancer.
2. How does Lenvatinib work against cancer?
Lenvatinib works by blocking multiple specific proteins (kinases) that cancer cells use to grow and form new blood vessels. By inhibiting these targets, including VEGF receptors, it effectively cuts off the tumor’s blood supply (anti-angiogenesis) and slows down its growth and spread.
3. Is Lenvatinib considered a form of chemotherapy? No, Lenvatinib is a targeted therapy. Unlike traditional chemotherapy, which attacks all fast-growing cells, Lenvatinib is designed to block specific molecular pathways that are crucial for the cancer’s survival, leading to a different set of potential side effects.
4. What are the common brand names for Lenvatinib in the Philippines?
The original and globally recognized brand name for Lenvatinib is Lenvima®, manufactured by Eisai. Generic versions may become available over time; it is best to consult with your oncologist about the specific formulations registered with the Philippine Food and Drug Administration (FDA).
Treatment, Side Effects, and Management
5. How is Lenvatinib taken?
Lenvatinib is an oral capsule taken once a day, at the same time each day. It can be taken with or without food. The dose, which may involve a combination of 4mg and 10mg capsules, will be carefully determined by your oncologist based on your specific cancer type and body weight.
6. What is the most common and important side effect to monitor with Lenvatinib? Hypertension (high blood pressure) is a very common and significant side effect. Your blood pressure must be well-controlled before starting treatment and monitored very closely throughout, especially during the first few weeks. Your doctor will prescribe blood pressure medication as needed.
7. What are other frequent side effects I should expect?
Other common side effects include severe diarrhea, fatigue, decreased appetite and weight loss, joint and muscle pain, nausea, and Hand-Foot Skin Reaction (HFSR), which causes redness and soreness on palms and soles.
8. How can I manage common side effects like severe diarrhea?
Diarrhea can be serious and lead to dehydration. It’s crucial to inform your doctor immediately. They will recommend anti-diarrheal medication, advise you to drink plenty of fluids, and suggest dietary changes.
9. What are the most serious risks associated with Lenvatinib?
Beyond severe hypertension, serious risks include cardiac problems (heart failure), arterial blood clots (leading to heart attack or stroke), liver injury (hepatotoxicity), kidney problems, and the risk of developing a hole or abnormal connection in the digestive tract (perforation or fistula).
Safety, Monitoring, and Access in the Philippines
10. How will my oncologist in the Philippines monitor my health during treatment?
You will require frequent and regular check-ups. This includes blood pressure monitoring (which you may need to do at home as well), regular blood tests to check your liver function, kidney function, and electrolyte levels, and urine tests to check for protein.
11. Should I stop taking Lenvatinib before any planned surgery?
Yes. Because Lenvatinib can interfere with wound healing, you must inform your doctor or surgeon that you are taking it before any planned surgical procedure. They will likely advise you to stop taking Lenvatinib for a specific period before and after the surgery.
12. Can Lenvatinib be taken during pregnancy?
No. Lenvatinib can cause serious harm to a developing fetus. Women who can become pregnant must have a negative pregnancy test before starting and use highly effective contraception during treatment and for at least 30 days after the final dose.
13. Are there any important drug or food interactions to be aware of?
Yes. Inform your doctor of all other medications you are taking. You should avoid grapefruit and grapefruit juice, as they can affect the levels of Lenvatinib in your body.
14. Where can patients in the Philippines obtain Lenvatinib capsules? Lenvatinib is a high-cost specialty medication. It is not available in regular local drugstores. It is dispensed through major hospital pharmacies, cancer centers, or authorized specialty pharmaceutical distributors in the Philippines.
15. How can Filipino patients find financial assistance for the high cost of Lenvatinib?
Navigating the cost is a major concern. Patients and their families in the Philippines should:
- Inquire with the Philippine Health Insurance Corporation (PhilHealth) about coverage under specific benefit packages.
- Seek assistance from the Philippine Charity Sweepstakes Office (PCSO) and the Department of Social Welfare and Development (DSWD), which provide medical assistance programs.
- Ask their oncologist or the hospital’s social work department about any Patient Access Programs run by the pharmaceutical company (Eisai), which may offer the drug at a subsidized cost or provide other forms of support.
Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Lenvatinib is a potent prescription medication. Always consult your medical oncologist for diagnosis, treatment, and any questions you may have regarding your medical condition.
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