Microsphere Tretinoin Gel 0.025% (MyTret) is a prescription-strength retinoid treatment designed to help manage acne, reduce post-acne marks, smooth fine lines, and improve overall skin texture. Using microsphere technology, it releases tretinoin slowly into the skin, offering better tolerability and reduced irritation, making it suitable for sensitive or tropical-climate skin, like commonly seen in the Philippines.
🧪 How Microsphere Tretinoin Works
| Ingredient | Mechanism |
|---|---|
| Tretinoin 0.025% | Increases skin cell turnover, unclogs pores, improves collagen production |
| Microsphere delivery system | Slow release → less irritation & enhanced penetration |
🌴 Why it’s ideal for Philippine skin conditions
✔ Sweat-resistant (useful in humidity)
✔ Less irritation compared to standard tretinoin
✔ Targets oily & acne-prone skin common in Filipino population
✔ Helps fade acne scars & hyperpigmentation over time
📌 How to Use
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Apply only at night, pea-sized amount.
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Start every alternate night for 2 weeks.
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Always follow with broad-spectrum SPF 30–50 during the day.
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Don’t combine with scrubs, waxing, harsh actives the same night.
⚠ Safety & Regulatory Note (Philippines)
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Tretinoin (Retinoic Acid) is classified as a prescription-only drug active by FDA Philippines.
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Must only be used under dermatologist supervision.
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Not recommended for pregnant or breastfeeding women.
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Initial purging may occur for 2–4 weeks.
🔹 FAQs (10)
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What is Microsphere Tretinoin 0.025% Gel used for?
For acne treatment, skin renewal, and improving texture. -
How is microsphere tretinoin different from regular tretinoin?
It releases the ingredient slowly, reducing irritation. -
Is it safe for Filipino oily skin?
Yes, ideal for acne-prone and humid-climate skin types. -
When should I apply it?
Only at night, on clean and dry skin. -
Do I need sunscreen the next day?
Absolutely. Retinoids increase sun sensitivity. -
Is microsphere tretinoin safer for sensitive skin?
Generally better tolerated, but mild irritation is common initially. -
Can I use it daily?
Start alternate nights, then daily if tolerated. -
Will it help acne scars and dark spots?
Yes, it boosts cell turnover and fades pigmentation gradually. -
Can pregnant women use tretinoin?
It is usually avoided during pregnancy. Consult a doctor. -
How long until I see results?
Visible improvement often in 6–12 weeks with regular use.
External Authority Links (Philippines)
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FDA Philippines – https://www.fda.gov.ph
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Philippine Dermatological Society – https://pds.org.ph
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DOH Philippines – https://doh.gov.ph
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WHO – Skin Health in Southeast Asia – https://www.who.int
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FDA Advisory on retinoids – https://www.fda.gov.ph/fda-advisories/


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