Tinat 20

Product Introduction

Tinat 20 Tablet is a pharmaceutical-grade, oral lipid-lowering agent containing the active ingredient Atorvastatin Calcium at a strength of 20mg. As a member of the HMG-CoA reductase inhibitor (statin) class, it is a globally recognized and essential medication used for the management of hypercholesterolemia and the prevention of cardiovascular disease. This product is supplied for bulk distribution to support extensive public and private healthcare needs.

Uses of Tinat 20 Tablet Tinat 20 Tablet is primarily indicated for the following conditions:

• Hypercholesterolemia: To reduce elevated total cholesterol, LDL-C (Low-Density Lipoprotein Cholesterol or “bad” cholesterol), and triglycerides in adult patients with primary hypercholesterolemia, mixed dyslipidemia, and homozygous familial hypercholesterolemia, when diet and lifestyle changes alone are insufficient.
• Cardiovascular Disease Prevention: To reduce the risk of non-fatal myocardial infarction (heart attack), stroke, and the need for revascularization procedures in adult patients with multiple risk factors but without clinically evident coronary heart disease.

Benefits of Tinat 20 Tablet Tinat 20 Tablet is highly preferred in clinical practice due to its advantages:

• Potent Lipid Reduction: Atorvastatin is one of the most effective statins, achieving significant reductions in LDL-C, which is the primary therapeutic goal for cardiovascular risk reduction.
• Cardioprotective Effects: Beyond cholesterol lowering, Atorvastatin provides pleiotropic benefits, including improving endothelial function, stabilizing atherosclerotic plaques, and exhibiting anti-inflammatory and anti-oxidative effects, thereby significantly reducing the risk of major cardiovascular events.
• Convenient Dosing: The 20mg strength is a common and effective dose for many patient profiles, offering once-daily administration which aids patient compliance.

Side Effects of Tinat 20 Tablet While generally well-tolerated, Tinat 20 Tablet may cause side effects, with some requiring immediate medical attention.

• Common Side Effects: Headache, nasopharyngitis, gastrointestinal issues (nausea, diarrhea, indigestion), back pain, and joint pain (arthralgia).
• Serious Side Effects (Rare but important warnings):
  • Myopathy/Rhabdomyolysis: Muscle pain, tenderness, or weakness, especially if accompanied by fever or malaise.
  • Hepatotoxicity: Liver problems, indicated by unexplained fatigue, dark urine, or yellowing of the skin/eyes (jaundice).
  • Diabetes Risk: Small increase in the risk of new-onset diabetes mellitus.

Disclaimer: This is not an exhaustive list. Medical consultation is mandatory for complete assessment.

How to Use Tinat 20 Tablet

• Dosage: The typical starting dose of Atorvastatin is $10\text{ mg}$ or $20\text{ mg}$ once daily. The $20\text{ mg}$ strength is often used as a standard initial or maintenance dose. Dosage must be individualized based on LDL-C levels and therapeutic goals.
• Administration: The tablet should be taken orally, once daily, at any time of day, and can be taken with or without food. Consistent daily timing is recommended for maintaining routine.
• Compliance: Treatment is typically long-term, and patients must be advised to adhere strictly to the low-fat, cholesterol-lowering diet recommended by their physician.

How Tinat 20 Tablet Works Tinat 20 Tablet contains Atorvastatin, which is a selective and competitive inhibitor of HMG-CoA reductase. This enzyme catalyzes the conversion of $\text{HMG-CoA}$ to mevalonate, an early and rate-limiting step in cholesterol biosynthesis in the liver. By blocking this enzyme, Atorvastatin reduces the amount of cholesterol produced by the liver. This reduction causes the liver to increase the number of $\text{LDL}$ receptors on the surface of its cells, which enhances the uptake and removal of $\text{LDL}$ cholesterol from the bloodstream, thereby lowering overall plasma cholesterol levels.

• Liver Monitoring: Liver function tests ($\text{LFTs}$) should be performed prior to initiating therapy and monitored periodically thereafter. Discontinue if $\text{ALT}$ or $\text{AST}$ levels persist at $\ge 3$ times the upper limit of normal ($\text{ULN}$).
• Myopathy/Rhabdomyolysis Risk: The risk is increased when taken with certain drugs (e.g., strong $\text{CYP}3\text{A}4$ inhibitors, fibrates). Patients must report any unexplained muscle pain or weakness immediately.
• Pregnancy & Lactation: Tinat 20 Tablet is strictly contraindicated in pregnant and breastfeeding women.
• Women of childbearing potential must use effective contraception during treatment.
• Alcohol: Excessive alcohol consumption should be avoided due to the potential for liver toxicity.
• Contraindications: Contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases.

What if You Forget to Take Tinat 20 Tablet?

If a patient misses a dose, they should take it as soon as they remember, unless it is already time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular schedule should be continued. Patients must not double the dose to make up for a missed one.

Quick Tips

• Consistency is Key: Take the tablet once daily at a consistent time to help adherence.
• Dietary Adherence: Stress the importance of continuing the prescribed diet alongside medication.
• Muscle Pain Warning: Advise patients to be vigilant for and immediately report any severe muscle aches or weakness.
• Grapefruit Warning: Avoid consuming large amounts of grapefruit juice, as it can increase drug levels and the risk of side effects.

FAQs

Q1: What makes Tinat 20 Tablet an essential bulk item for international supply?

A: Tinat 20 (Atorvastatin 20mg) is listed on the WHO Model List of Essential Medicines and is a high-volume, continuously demanded drug for chronic cardiovascular disease management globally. Its high clinical efficacy and cost-effectiveness ensure consistent demand across all major markets, including Australia, Germany, Singapore, the UK, the US, and the Philippines.

Q2: What is the recommended storage condition for bulk orders of Tinat 20 Tablet?

A: Tinat 20 Tablet should be stored at controlled room temperature, typically between 20∘C to 25∘C (68∘F to 77∘F), protected from excessive moisture and heat. Our bulk packaging and international shipping procedures ensure the maintenance of these conditions to preserve product integrity and shelf life.

Q3: Is the 20mg strength suitable for all patients with hypercholesterolemia?

A: The $20\text{ mg}$ strength is often a standard effective dose for many patients. However, the exact dosage must be individualized. Bulk buyers should stock a range of strengths ($\text{e.g., }10\text{ mg},40\text{ mg},80\text{ mg}$) to meet diverse patient needs and titration requirements as per physician prescription.

Q4: How does palmerwellnesshub ensure compliance with international pharmaceutical regulations for this product?

A: We provide full regulatory support, including Certificates of Analysis ($\text{CoA}$), GMP certifications, and country-specific documentation to confirm that Tinat 20 Tablet meets the necessary quality and safety standards for import and distribution in all listed territories.

Q5: What are the key drug-drug interactions that suppliers should flag for this product?

A: The most critical interactions involve $\text{CYP}3\text{A}4$ inhibitors (e.g., itraconazole, clarithromycin, HIV protease inhibitors), which can significantly increase Atorvastatin levels, raising the risk of myopathy. Co-administration with Gemfibrozil or other fibrates also increases muscle-related side effect risks and requires extreme caution.

Q6: Can Tinat 20 Tablet be used for pediatric patients?

A: Atorvastatin is generally indicated for adults. It may be used in pediatric patients ($\ge 10$ years of age) with heterozygous familial hypercholesterolemia, but only under specialist guidance and with a modified, lower dosage regimen. Bulk suppliers should note that pediatric use represents a smaller, specialized segment of the market.

A Note to Our Bulk Buyers:

palmerwellnesshub is dedicated to delivering pharmaceutical-grade Tinat 20 Tablet with exceptional quality control. We offer this highly demanded, essential cardiovascular medication for bulk supply with guaranteed efficient and compliant international shipping to our partners in Australia, Germany, Singapore, the UK, the US, and the Philippines.