Enzalutamide Capsules/Tablets – 40mg / 80mg / 160mg

🔬 About Enzalutamide

Enzalutamide is a next-generation anti-androgen therapy prescribed to patients with advanced prostate cancer. It works by blocking androgen receptors, which helps in slowing or stopping the growth of cancer cells that depend on androgens (male hormones).

It is often used in castration-resistant prostate cancer (CRPC) — both metastatic (mCRPC) and non-metastatic (nmCRPC) — with or without prior chemotherapy.

💊 Available Dosages:

• Enzalutamide 40mg Capsules

• Enzalutamide 80mg Tablets

• Enzalutamide 160mg Tablets

Choose your dosage as advised by your oncologist. Available in blister packs and HDPE bottles.

✅ Key Features & Benefits:

• Highly effective in hormone therapy-resistant prostate cancer

• Oral therapy – convenient & patient-friendly

• Used globally in advanced-stage oncology protocols

• Can be used alongside GnRH analogs or surgical castration

🧬 How Enzalutamide Works:

Enzalutamide directly inhibits the androgen receptor pathway, preventing testosterone from fueling tumor growth. This helps in reducing PSA levels and delaying disease progression.

🛒 Why Buy From PalmerWellness.com?

• Authentic Anti-Cancer Medicines

• Affordable prices, secure payment, and global delivery

• Trusted by oncologists and cancer care centers worldwide

• Personalized support & guidance for each patient

🧴 Storage Instructions:

• Store at room temperature (15–30°C)

• Keep away from direct sunlight and moisture

• Keep out of reach of children

Of course. Here are 20 frequently asked questions (FAQs) about Enzalutamide, with a global perspective relevant to patients in the Philippines and other countries, excluding India.

Frequently Asked Questions (FAQ) for Enzalutamide

1. What is Enzalutamide and what is its primary use? Enzalutamide is a powerful oral medication used to treat prostate cancer. It is specifically an androgen receptor inhibitor, designed to slow the growth and spread of prostate cancer that is driven by male hormones (androgens).

2. How does Enzalutamide work to fight prostate cancer? Prostate cancer cells often use male hormones like testosterone as “fuel” to grow. Enzalutamide works by blocking this fuel supply at multiple points. It prevents testosterone from binding to its receptor on the cancer cells, stops the receptor from signaling the cell to grow, and impairs its ability to interact with the cell’s DNA.

3. What specific types of prostate cancer is Enzalutamide approved for? Its approved uses typically include various stages of advanced prostate cancer, such as metastatic castration-resistant prostate cancer (mCRPC), non-metastatic castration-resistant prostate cancer (nmCRPC), and metastatic castration-sensitive prostate cancer (mCSPC), among others. The exact indication depends on your medical history and country’s regulatory approvals.

4. Is Enzalutamide considered chemotherapy or hormone therapy? Enzalutamide is a type of hormone therapy (also called endocrine therapy). Unlike traditional chemotherapy, which kills rapidly dividing cells throughout the body, Enzalutamide specifically targets the hormonal pathway that fuels prostate cancer growth.

5. How is Enzalutamide typically taken? The standard dose is 160 mg taken orally once a day. It can be taken with or without food. The capsules or tablets should be swallowed whole. Always follow the precise instructions given by your oncologist.

6. What should I do if I miss a dose? If you miss a dose, take it as soon as you remember on the same day. If you miss your dose for the entire day, skip the missed dose and resume your regular schedule the next day. Do not take an extra dose to make up for the one you missed.

7. Can I crush, chew, or open the capsules or tablets? No. You should swallow the medication whole with water. Crushing or opening the capsules can alter how the drug is absorbed and may expose the handler to the active ingredient.

8. What are the most common side effects of Enzalutamide? Common side effects include severe fatigue (asthenia), hot flashes, muscle and joint pain, back pain, headache, high blood pressure (hypertension), and diarrhea. It’s important to report these to your doctor, who can help you manage them.

9. What are the most serious risks I should watch out for? While less common, serious risks require immediate medical attention. These include seizures, a rare brain condition called PRES (symptoms include severe headache, vision changes, confusion), ischemic heart disease (heart attack, chest pain), and an increased risk of falls and bone fractures.

10. Why is there a risk of seizures with this medication? Enzalutamide can affect the central nervous system and lower the seizure threshold, making a seizure more likely, especially in individuals with a prior history of seizures, brain injury, or stroke. Inform your doctor of any such history before starting treatment.

11. The fatigue from Enzalutamide is very strong. How can I manage it? Fatigue is a very common side effect. To manage it, try to maintain a consistent sleep schedule, engage in light physical activity like walking (as approved by your doctor), stay hydrated, and eat a balanced diet. Prioritize your tasks and allow yourself to rest when needed.

12. Why is using effective contraception so important while taking Enzalutamide? This is a critical safety issue. Enzalutamide can cause serious harm to a developing fetus. Male patients with female partners who can become pregnant must use effective contraception (such as a condom) during the entire treatment period and for at least 3 months after the final dose.

13. Can Enzalutamide interact with other medications I take? Yes. Enzalutamide can interact with many other drugs, including certain blood thinners (like warfarin), heart medications, and even herbal supplements like St. John’s Wort. Always provide your oncologist with a complete list of every medication, vitamin, and supplement you are taking.

14. Are there any specific foods or supplements I should avoid? You should avoid grapefruit and grapefruit juice, as they can interfere with how the drug is metabolized in your body. Also, avoid taking any new supplements, especially St. John’s Wort, without first consulting your doctor.

15. Is it safe to drink alcohol while on Enzalutamide? It is best to discuss alcohol consumption with your doctor. Alcohol can worsen side effects like fatigue and dizziness and may increase the risk of falls.

16. How long will I need to be on this treatment? Enzalutamide is typically taken on a continuous basis for as long as it is effectively controlling the cancer and the side effects are manageable. The duration of your treatment will be determined by your oncologist based on your response and regular monitoring.

17. How will my doctor monitor my progress on this medication? Your doctor will monitor you regularly through blood tests, primarily the Prostate-Specific Antigen (PSA) test, to see how the cancer is responding. They will also monitor your blood pressure and may order imaging scans (like CT or bone scans) periodically.

18. What are the common brand names for Enzalutamide worldwide? The original and most widely known global brand name for Enzalutamide is Xtandi®. In some countries, generic versions may become available over time under different brand names. Always ensure your medication is sourced from a reputable pharmacy.

19. Is Enzalutamide covered by insurance or national health systems like PhilHealth in the Philippines? Coverage for high-cost cancer medications like Enzalutamide varies greatly depending on your country’s national health system and your private insurance plan. In the Philippines, patients should directly consult with PhilHealth and their insurance provider to determine the extent of coverage, reimbursement policies, and any out-of-pocket costs. Hospital social workers can often assist with this process.

20. What lifestyle changes can help support my health during treatment? Maintaining a healthy lifestyle is beneficial. This includes eating a balanced diet rich in fruits and vegetables, engaging in gentle exercise as approved by your doctor to combat fatigue and maintain muscle mass, staying hydrated, and maintaining open communication with your healthcare team and loved ones.

External Reference Links:

1. https://www.cancer.gov/about-cancer/treatment/drugs/enzalutamide

2. https://www.webmd.com/drugs/2/drug-165048/enzalutamide-oral/details

3. https://www.drugs.com/mtm/enzalutamide.html

4. https://medlineplus.gov/druginfo/meds/a613042.html

5. https://prostatecanceruk.org/prostate-information-and-support/treatments/enzalutamide